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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • H11-CAG-LSL-Myc

    H11-CAG-LSL-Myc

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Application : Tumor-Bearing M
    • KI/KO Gene : Igs2
    • Synonyms : H11,Hipp11,Iis2
  • Inppl1-KO

    Inppl1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Exon : Exon 5
    • Application : Cancer Related;
    • Disease : Type 2 Diabetes
  • Ifng-KO

    Ifng-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-If
    • Exon : Exon 1-4.
    • Application : Cancer Related;
    • Disease : Malaria
  • Lrp1-Flox

    Lrp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon  7-8 of
    • Application : Cancer Related;
    • Disease : Cardiomyopathy
  • Lrfn2-KO

    Lrfn2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon 2
    • Application : Cancer Related;
    • Disease : Autism Spectrum
  • Mdk-KO

    Mdk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Md
    • Exon : Exon 3-4
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Mc3r-KO

    Mc3r-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mc
    • Exon : Exon 1
    • Application : Obesity
    • Disease : Obesity
  • Mybpc3-KO

    Mybpc3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-My
    • Exon : Exon 3-5
    • Application : Obesity
    • Disease : Hypertrophic Ca
  • Med1-Flox

    Med1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon s
    • Application : Obesity
    • Disease : Dilated Cardiom
  • Nr5a1-Flox

    Nr5a1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 4
    • Application : Research On Gen
    • Disease : Hypogonadotropi
  • Npy1r-KO

    Npy1r-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 2
    • Application : Endocrine And M
    • Disease : Obesity
  • Nos3-KO

    Nos3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Exon : Exon 10-11
    • Application : Endocrine And M
    • Disease : Hypertrophic Ca
  • Pdgfrb-Flox

    Pdgfrb-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon 3-7
    • Application : Ret Signal Tran
    • Disease : Autism Spectrum
  • Plcb1-KO

    Plcb1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pl
    • Exon : Exon 7
    • Application : Ret Signal Tran
    • Disease : Alzheimer's dis
  • Prkn-KO

    Prkn-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 3.
    • Application : Immune-Related
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hFGFR2*S320C-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : D-2-Hydroxyglut
  • R26-CAG-LSL-hHER2*ex20ins-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 20
    • Application : Cancer Research
    • Disease : D-2-Hydroxyglut
  • R26-CAG-LSL-hTM6SF2*E167K-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 20
    • Application : Non-Alcoholic F
    • Disease : D-2-Hydroxyglut
  • Senp1-Flox

    Senp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Se
    • Exon : Exon 4
    • Application : Non-Alcoholic F
    • Disease : Type 1 Diabetes
  • Rrn3-Flox

    Rrn3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Rr
    • Exon : Exon s
    • Application : Non-Alcoholic F
    • Disease : Parkinson's Dis
  • Raf1-D486N

    Raf1-D486N

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ra
    • Exon : Exon s
    • Application : Noonan Syndrome
    • Disease : Parkinson's Dis