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Srf-Flox

SKU : BHAM00312

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Srf gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Srf gene. Official Symbol: Srf NCBI ID: 20807 MGI ID: 106658 Ensembl ID: ENSMUSG00000015605 Pubmed: Srf Human Ortholog: SRF
Nomenclature	C57BL/6JSmoc-Srf^{em1(flox)Smoc}
Exon	Exon s
Disease	Dilated Cardiomyopathy
Disease	Cardio-metabolic Disease
KI/KO Gene	Srf
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Myh6-cre mice.
Synonyms	AW049942, AW240594

Reference	MGI:5465282 Parlakian A, Charvet C, Escoubet B, Mericskay M, Molkentin JD, Gary-Bobo G, De Windt LJ, Ludosky MA, Paulin D, Daegelen D, Tuil D, Li Z, Temporally controlled onset of dilated cardiomyopathy through disruption of the SRF gene in adult heart. Circulation. 2005 Nov 8;112(19):2930-9

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