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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Slc6a4-KO

    Slc6a4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3-4
    • Disease : Autism Spectrum
    • KI/KO Gene : Slc6a4
  • Srgap3-KO

    Srgap3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sr
    • Exon : Exon 3
    • Disease : Schizophrenia
    • KI/KO Gene : Srgap3
  • Taar1-KO

    Taar1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ta
    • Exon : Exon 1
    • Disease : Schizophrenia
    • KI/KO Gene : Taar1
  • Stat3-Flox

    Stat3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 12-14
    • Application : Cancer Research
    • Disease : Inflammatory Bo
  • Tmprss9-KO

    Tmprss9-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 3
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Tmem173-V154M

    Tmem173-V154M

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tm
    • Exon : Exon 3
    • Application : Sting-Associate
    • Disease : Autism Spectrum
  • Uox-KO(2)

    Uox-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Uo
    • Exon : Exon 3-4.
    • Application : Hyperuricemia R
    • Disease : nephrogenic dia
  • Zmpste24-KO

    Zmpste24-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Uo
    • Exon : Exon 4-6
    • Application : Premature Aging
    • Disease : Achalasia
  • hACE2

    hACE2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ac
    • Exon : Exon 4-6
    • Application : Corona Virus Re
    • Disease : Achalasia
  • R26-CAG-LSL-hACE2-IRES-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 4-6
    • Application : Corona Virus Re
    • Disease : Achalasia
  • Adh7-KO

    Adh7-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Exon : Exon 3
    • Application : Corona Virus Re
    • Disease : Parkinson's Dis
  • Acadm-repeat(E8-10)

    Acadm-repeat(E8-10)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ac
    • Exon : Exon 10
    • Application : Medium Chain Ac
    • Disease : Medium Chain Ac
  • Apoa2-KO

    Apoa2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Homozygous Hype
  • Alpl-KO

    Alpl-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 3-4
    • Application : Therapeutic Ant
    • Disease : Childhood Hypop
  • Aldob-KO

    Aldob-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 3-6
    • Application : Hereditary Fruc
    • Disease : Hereditary Fruc
  • Bag3-Flox

    Bag3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ba
    • Exon : Exon 4
    • Application : Hereditary Fruc
    • Disease : Dilated Cardiom
  • Axl-KO

    Axl-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ax
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • App-KO

    App-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Exon : Exon 3
    • Application : Neuronal Differ
    • Disease : Alzheimer's Dis
  • C4b-KO

    C4b-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C4
    • Exon : Exon 3
    • Application : Inflammatory Re
    • Disease : Systemic Lupus
  • Brca1-Flox

    Brca1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Breast Cancer
  • Cdk4-KO

    Cdk4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 3-7
    • Application : The Protein Enc
    • Disease : Type 1 Diabetes
  • Cadps2-KO

    Cadps2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Exon : Exon 5-6
    • Application : The Protein Enc
    • Disease : Autism Spectrum
  • Daam1-Flox

    Daam1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Da
    • Exon : Exon s
    • Application : The Protein Enc
    • Disease : Intrinsic Cardi
  • Ctf1-KO

    Ctf1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ct
    • Exon : Exon 2
    • Application : The Protein Enc
    • Disease : Type 2 Diabetes
  • Dmp1-KO

    Dmp1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 4-6
    • Application : Research On The
    • Disease : Autosomal Reces