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Pdgfrb-Flox

SKU : BHAM00211

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200204
Description	Model Description: These mice carry loxP sites flanking exon 3-7 of Pdgfrb gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Pdgfrb gene. Official Symbol: Pdgfrb NCBI ID: 18596 MGI ID: 97531 Ensembl ID: ENSMUSG00000024620 Pubmed: Pdgfrb Human Ortholog: PDGFRB
Nomenclature	C57BL/6JSmoc-Pdgfrb^{tm1(flox)Smoc}
Exon	Exon 3-7
Application	Ret Signal Transduction And B Cell Receptor (Bcr) Downstream Signal Transduction Events Related Research
Disease	Autism Spectrum Disorder
Disease	Nervous System Disease
KI/KO Gene	Pdgfrb
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Nes-cre mice.
Synonyms	Pdgfr, CD140b, PDGFR-1, AI528809

Reference	MGI:4367213 Nakamura T, Matsumoto J, Takamura Y, Ishii Y, Sasahara M, Ono T, Nishijo H, Relationships among parvalbumin-immunoreactive neuron density, phase-locked gamma oscillations, and autistic/schizophrenic symptoms in PDGFR-beta knock-out and control mice. PLoS One. 2015;10(3):e0119258

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