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Arx-Flox

SKU : BHAM00025

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	TBD
Description	Model Description: These mice carry loxP sites flanking target exons of Arx gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Arx gene. Official Symbol: Arx NCBI ID: 11878 MGI ID: 1097716 Ensembl ID: ENSMUSG00000035277 Pubmed: Arx Human Ortholog: ARX
Nomenclature	C57BL/6JSmoc-Arx^{em1(flox)Smoc}
Exon	Exon s
Disease	Early Infantile Epileptic Encephalopathy
Disease	Nervous System Disease
KI/KO Gene	Arx
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with mI56i-cre mice.
Synonyms	Arx1

Reference	MGI:3606580 Marsh E, Fulp C, Gomez E, Nasrallah I, Minarcik J, Sudi J, Christian SL, Mancini G, Labosky P, Dobyns W, Brooks-Kayal A, Golden JA, Targeted loss of Arx results in a developmental epilepsy mouse model and recapitulates the human phenotype in heterozygous females. Brain. 2009 Jun;132(Pt 6):1563-76

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