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Nr5a1-Flox

SKU : BHAM00203

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200071
Description	Model Description: These mice carry loxP sites flanking exon 4 of Nr5a1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Nr5a1 gene. Official Symbol: Nr5a1 NCBI ID: 26423 MGI ID: 1346833 Ensembl ID: ENSMUSG00000026751 Pubmed: Nr5a1 Human Ortholog: NR5A1
Nomenclature	C57BL/6JSmoc-Nr5a1^{em1(flox)Smoc}
Exon	Exon 4
Application	Research On Gene Expression And Aldosterone Synthesis And Secretion
Disease	Hypogonadotropic Hypogonadism
Disease	Rare Disease
KI/KO Gene	Nr5a1
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Cga-cre mice.
Synonyms	ELP, SF1, SF-1, Ad4BP, ELP-3, Ftzf1, STF-1, Ftz-F1

Reference	MGI:4461155 Zhao L, Bakke M, Krimkevich Y, Cushman LJ, Parlow AF, Camper SA, Parker KL, Steroidogenic factor 1 (SF1) is essential for pituitary gonadotrope function. Development. 2001 Jan;128(2):147-54

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