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Dag1-Flox

SKU : BHAM00061

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-230140
Description	Model Description: These mice carry loxP sites flanking exon 4 of Dag1 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Dag1 gene. Official Symbol: Dag1 NCBI ID: 13138 MGI ID: 101864 Ensembl ID: ENSMUSG00000039952 Pubmed: Dag1 Human Ortholog: DAG1
Nomenclature	C57BL/6JSmoc-Dag1^{em(flox)/Smoc}
Exon	Exon 4
Disease	Dilated Cardiomyopathy
Disease	Cardio-metabolic Disease
KI/KO Gene	Dag1
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Myl2-Cre mice.
Synonyms	DG, Dp71, Dp427, D9Wsu13e

Reference	MGI:5467575 Michele DE, Kabaeva Z, Davis SL, Weiss RM, Campbell KP, Dystroglycan matrix receptor function in cardiac myocytes is important for limiting activity-induced myocardial damage. Circ Res. 2009 Nov 6;105(10):984-93

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