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Fas-KO(BALB/c)

SKU : BHAM00096

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KO-191206
Description	Model Description: Exon 2 of Fas gene was deleted to generate Fas knockout mice. Official Symbol: Fas NCBI ID: 14102 MGI ID: 95484 Ensembl ID: ENSMUSG00000024778 Pubmed: Fas Human Ortholog: FAS
Nomenclature	BALB/cAnSmoc-Fas^em2Smoc
Exon	Exon 2
Application	Immune-Related
Disease	Systemic Lupus Erythematosus
Disease	Autoimmune Disease
KI/KO Gene	Fas
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tnfrsf9-KO(2)(NM-KO-210216) mice.
Synonyms	lpr, APO1, APT1, CD95, TNFR6, Tnfrsf6, AI196731

Reference	MGI:3690327 Ohta A, Sekimoto M, Sato M, Koda T, Nishimura S, Iwakura Y, Sekikawa K, Nishimura T, Indispensable role for TNF-alpha and IFN-gamma at the effector phase of liver injury mediated by Th1 cells specific to hepatitis B virus surface antigen. J Immunol. 2000 Jul 15;165(2):956-61

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