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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Dmpk-KO

    Dmpk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 1-7
    • Application : Cardiac Conduct
    • Disease : Myotonic Dystro
  • Dmd-Q995X

    Dmd-Q995X

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dm
    • Exon : Exon 1-7
    • Application : Cardiac Conduct
    • Disease : Duchenne muscul
  • Des-KO

    Des-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-De
    • Exon : Exon 2-5
    • Application : Immune-Related
    • Disease : Duchenne muscul
  • Dbt-KO

    Dbt-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Db
    • Exon : Exon 2
    • Application : Studies On Degr
    • Disease : Maple Syrup Uri
  • Ext1-Flox

    Ext1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ex
    • Exon : Exon s
    • Application : Studies On Degr
    • Disease : Hereditary Mult
  • Fem1b-KO

    Fem1b-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ex
    • Exon : Exon 2
    • Application : Mediating Apopt
    • Disease : Type 2 Diabetes
  • F8-KO(2)

    F8-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F8
    • Exon : Exon 1-26.
    • Application : Hemophilia A;He
    • Disease : factor VIII def
  • G6pc-Flox

    G6pc-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-G6
    • Exon : Exon 3
    • Application : Diseases Associ
    • Disease : Glycogen Storag
  • Ghr-KO(2)

    Ghr-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gh
    • Exon : Exon 1-7.
    • Application : Peptide Ligand
    • Disease : Laron syndrome
  • Gck-Flox

    Gck-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gc
    • Exon : Exon s
    • Application : Peptide Ligand
    • Disease : Familial Hyperi
  • Gcdh-KO

    Gcdh-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gc
    • Exon : Exon 3-7
    • Application : Glutaric Acidem
    • Disease : Glutaric Acidem
  • Gbe1-KO

    Gbe1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gb
    • Exon : Exon 2
    • Application : Glutaric Acidem
    • Disease : Glycogen Storag
  • Gba-Flox

    Gba-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gb
    • Exon : Exon 8-11
    • Application : Gaucher Disease
    • Disease : Gaucher's Disea
  • Hnf4a-Flox

    Hnf4a-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hn
    • Exon : Exon 2.
    • Application : Transcriptional
    • Disease : Fanconi Syndrom
  • Hif1a-Flox

    Hif1a-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hi
    • Exon : Exon 2
    • Application : Hypoxia-Inducib
    • Disease : Von Hippel-Lind
  • Ikzf3-KO

    Ikzf3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ik
    • Exon : Exon 8
    • Application : Hypoxia-Inducib
    • Disease : Systemic Lupus
  • Krt14-R131C

    Krt14-R131C

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kr
    • Exon : Exon 8
    • Application : Skin Diseases R
    • Disease : epidermolysis b
  • KPC

    KPC

    KPC

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 8
    • Application : Spontaneous Pan
    • Disease : Pancreatic Carc
  • Lmx1a-Flox

    Lmx1a-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon s
    • Application : Spontaneous Pan
    • Disease : Parkinson's Dis
  • Lmna-c.C1827T

    Lmna-c.C1827T

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon s
    • Application : Spontaneous Pan
    • Disease : Progeria
  • Lepr-KO

    Lepr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Le
    • Exon : Exon 5
    • Application : Obesity
    • Disease : Type 2 Diabetes
  • Mc4r-KO

    Mc4r-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mc
    • Exon : Exon 1
    • Application : Therapeutic Ant
    • Disease : obesity
  • Map6-KO

    Map6-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon 2
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Mafa-KO

    Mafa-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon 1
    • Application : Therapeutic Ant
    • Disease : type 2 diabetes
  • Madd-Flox

    Madd-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon s
    • Application : Therapeutic Ant
    • Disease : Type 2 Diabetes