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Usp1-Flox

SKU : BHAM00345

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200052
Description	Model Description: These mice carry loxP sites flanking exon 3 of Usp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Usp1 gene. Official Symbol: Usp1 NCBI ID: 230484 MGI ID: 2385198 Ensembl ID: ENSMUSG00000028560 Pubmed: Usp1 Human Ortholog: USP1
Nomenclature	C57BL/6JSmoc-Usp1^{em1(flox)Smoc}
Exon	Exon 3
Application	Diseases Associated With Usp1 Include Glioblastoma Proneural Subtype And Fanconi Anemia, Complementation Group I.
Disease	Fanconi Anemia Complementation Group D2
Disease	Rare Disease
KI/KO Gene	Usp1

Reference	Kim JM, et al., Inactivation of murine Usp1 results in genomic instability and a Fanconi anemia phenotype. Dev Cell. 2009 Feb;16(2):314-20

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