Model Description: Exon 6-7 of Prex1 gene was deleted to generate Prex1 knockout mice.
Official Symbol: Prex1
NCBI ID: 277360
MGI ID: 3040696
Ensembl ID: ENSMUSG00000039621
Pubmed: Prex1
Human Ortholog: PREX1
Nomenclature
C57BL/6JSmoc-Prex1em1Smoc
Exon
Exon 6-7
Disease
Autism Spectrum Disorder
Disease
Nervous System Disease
KI/KO Gene
Prex1
Synonyms
Setd6, P-REX1, G630042G04
Reference
Li J, Chai A, Wang L, Ma Y, Wu Z, Yu H, Mei L, Lu L, Zhang C, Yue W, Xu L, Rao Y, Zhang D, Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior. Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6964-72