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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • En2-KO

    En2-KO

    • Description : Model Descripti
    • Exon : Exon 1
    • Application : Therapeutic Ant
    • Disease : Autism Spectrum
    • KI/KO Gene : En2
  • Egln3-Flox

    Egln3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Eg
    • Exon : Exon 2-3
    • Application : Therapeutic Ant
    • Disease : cardiomyopathy
  • Fmo3-KO

    Fmo3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fm
    • Exon : Exon 3-6
    • Application : Therapeutic Ant
    • Disease : Fish-Odour Synd
  • F9-KO(2)

    F9-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F9
    • Exon : Exon 1-8.
    • Application : Hemophilia B
    • Disease : hemophilia B
  • Gadd45gip1-Flox

    Gadd45gip1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon s
    • Application : Hemophilia B
    • Disease : Type 2 Diabetes
  • G6pc-KO

    G6pc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-G6
    • Exon : Exon 3
    • Application : Hemophilia B
    • Disease : glycogen storag
  • Glul-Flox

    Glul-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Exon : Exon 4-7
    • Application : Hemophilia B
    • Disease : Temporal Lobe E
  • Gla-KO

    Gla-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Exon : Exon 2-3
    • Application : Fabry Disease R
    • Disease : Fabry Disease
  • Gucy2c-KO

    Gucy2c-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gu
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Obesity
  • Ins2-C96Y

    Ins2-C96Y

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Exon : Exon 3
    • Application : Diabetes Relate
    • Disease : Diabetes
  • Il33-KO(3)

    Il33-KO(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 2.
    • Application : Diabetes Relate
    • Disease : Alzheimer's dis
  • Il33-KO(2)

    Il33-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 3-7.
    • Application : Immune
    • Disease : Alzheimer's dis
  • Il10-KO(BALB/c)

    Il10-KO(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Il
    • Exon : Exon 1-5
    • Application : Research On Erk
    • Disease : Inflammatory Bo
  • kif18A-KO

    kif18A-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-kif18At
    • Exon : Exon 2
    • Application : Male Infertilit
    • Disease : Inflammatory Bo
  • Jakmip1-KO

    Jakmip1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ja
    • Exon : Exon 4-8
    • Application : Male Infertilit
    • Disease : Autism Spectrum
  • Irs1-KO

    Irs1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ir
    • Exon : Exon 1
    • Application : Diabetes Relate
    • Disease : Type 2 Diabetes
  • Lrrc10-KO

    Lrrc10-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon 1
    • Application : Diabetes Relate
    • Disease : Dilated Cardiom
  • Mus81-KO

    Mus81-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Exon : Exon 1-10
    • Application : Research On Hom
    • Disease : Marfan Syndrome
  • Mefv-hMEFV*V726A

    Mefv-hMEFV*V726A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 7-10
    • Application : Familial Medite
    • Disease : Familial Medite
  • Nos1-KO

    Nos1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Exon : Exon 3
    • Application : Familial Medite
    • Disease : Hypertrophic Ca
  • Nf2-Flox

    Nf2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nf
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Renal Cell Carc
  • Nexn-Flox

    Nexn-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • Neil1-KO

    Neil1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 2-3
    • Application : Cancer Research
    • Disease : Abdominal Obesi
  • Ncoa6-Flox

    Ncoa6-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nc
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • Park7-KO

    Park7-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pa
    • Exon : Exon 3-5
    • Application : A Sensor For Ox
    • Disease : Parkinson's Dis