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Plp1-Flox

SKU : BHAM00221

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-200072
Description	Model Description: These mice carry loxP sites flanking exon 3 of Plp1 gene. When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Plp1 gene. Official Symbol: Plp1 NCBI ID: 18823 MGI ID: 97623 Ensembl ID: ENSMUSG00000031425 Pubmed: Plp1 Human Ortholog: PLP1
Nomenclature	C57BL/6JSmoc-Plp1^{em1(flox)Smoc}
Exon	Exon 3
Application	The Study Of Glial Cell Differentiation And The Susceptibility Pathway Of Sudden Infant Death Syndrome (Sids)
Disease	Hereditary Spastic Paraplegia 2
Disease	Rare Disease
KI/KO Gene	Plp1
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Cnp-Cre mice.
Synonyms	jp, Plp, msd, rsh, DM20, jimpy

Reference	MGI:4843917 Luders KA, Patzig J, Simons M, Nave KA, Werner HB, Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2. Glia. 2017 Nov;65(11):1762-1776

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SKU	Supplier No.	Your price	Quantity
BHAM00221	NM-CKO-200072	-		Add to Quote

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