Model Description: These mice carry loxP sites flanking exon 2-3 of Mapk1 When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Mapk1 gene.
Official Symbol: Mapk1
NCBI ID: 26413
MGI ID: 1346858
Ensembl ID: ENSMUSG00000063358
Pubmed: Mapk1
Human Ortholog: MAPK1
Nomenclature
C57BL/6JSmoc-Mapk1em(flox)Smoc
Exon
Exon 2-3
Disease
Autism Spectrum Disorder
Disease
Nervous System Disease
KI/KO Gene
Mapk1
Notes
Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Nes-cre mice.
Satoh Y, Endo S, Nakata T, Kobayashi Y, Yamada K, Ikeda T, Takeuchi A, Hiramoto T, Watanabe Y, Kazama T, ERK2 contributes to the control of social behaviors in mice. J Neurosci. 2011 Aug 17;31(33):11953-67