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Home / Animal Model / Disease Mice

H11-CAG-LSL-Mycn-IRES-EGFP

SKU : BHAM00124

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KI-190084
Description	Model Description: These mice harbor a CAG-LSL-HA tag-Mycn-IRES-EGFP cassette in the lgs2 locus generated by homologous recombination. Official Symbol: Igs2 MGI ID: 5461148 Pubmed: Igs2
Nomenclature	C57BL/6JSmoc-Igs2^{em1(CAG-LSL-HAtag-Mycn-IRES-EGFP)Smoc}
Application	Cancer Research
Disease	Neuroblastoma
KI/KO Gene	Igs2
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Dbh-icre mice.
Synonyms	H11,Hipp11,Iis2

Reference	Althoff K, Beckers A, Bell E, Nortmeyer M, Thor T, Sprussel A, Lindner S, De Preter K, Florin A, Heukamp LC, Klein-Hitpass L, Astrahantseff K, Kumps C, Speleman F, Eggert A, Westermann F, Schramm A, Schulte JH, A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies. Oncogene. 2015 Jun;34(26):3357-68

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