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Home / Animal Model / Disease Mice

R26-CAG-LSL-hPIK3CA*H1047R-IRES-Luc-2A-tdTomato

SKU : BHAM00290

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-KI-190065
Description	Model Description: These mice harbor a CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato cassette in the Rosa26 locus generated by homologous recombination. Official Symbol: Gt(ROSA)26Sor NCBI ID: 14910 MGI ID: 104735 Ensembl ID: ENSMUSG00000086429 Pubmed: Gt(ROSA)26Sor
Nomenclature	C57BL/6JSmoc-Gt(ROSA)26Sor^{em1(CAG-LSL-PIK3CA(H1047R)-IRES-luciferase-2A-tdTomato)Smoc}
Application	Cancer Research
Disease	Breast Cancer
KI/KO Gene	Gt(ROSA)26Sor
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with MMTV-cre mice.
Synonyms	R26,ROSA26,AV258896,Gtrgeo26,Gtrosa26,Thumpd3as1

Reference	Adams JR, Xu K, Liu JC, Agamez NM, Loch AJ, Wong RG, Wang W, Wright KL, Lane TF, Zacksenhaus E, Egan SE, Cooperation between Pik3ca and p53 Mutations in Mouse Mammary Tumor Formation. Cancer Res. 2011 Apr 1;71(7):2706-2717

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