The ETO probe was labeled with orange-red dye, and the AML1 probe was labeled with green dye, and the two probes were combined to the target detection site by in situ hybridization.
Description
hematological tumor
Clinical Significance
The AML1/ETO gene fusion can be used as a secondary diagnosis of AML and a means of assessing prognosis. Clinically, t(8;21) leukemia represents a type of acute leukemia with good prognosis. Adult patients have good response to treatment, high complete remission rate, long median survival time, but easy recurrence; children's treatment and prognosis are not as good as adult patients. .