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Disease Mice

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Pdlim5-Flox

    Pdlim5-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon s
    • Disease : Dilated Cardiom
    • KI/KO Gene : Pdlim5
  • Pnliprp1-KO

    Pnliprp1-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Pnliprp
    • Exon : Exon 1
    • Application : Diabetes And Ob
    • Disease : Dilated Cardiom
  • Psen1-KO

    Psen1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ps
    • Exon : Exon 4
    • Application : Diabetes And Ob
    • Disease : Systemic Lupus
  • Psen1-Flox

    Psen1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ps
    • Exon : Exon s
    • Application : Diabetes And Ob
    • Disease : Alzheimer's Dis
  • Prlh-KO

    Prlh-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 2
    • Application : Diabetes And Ob
    • Disease : Obesity
  • Prex1-KO

    Prex1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 6-7
    • Application : Diabetes And Ob
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hBCR/ABL

    R26-CAG-LSL-hBCR/ABL

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Chronic Myelocy
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hNFE2L2*G81S-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Shank3-KO

    Shank3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sh
    • Exon : Exon 4-9
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Scarb2-KO

    Scarb2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sc
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Progressive Myo
  • R26-LSL-Notch1C-IRES-nEGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Spontaneous Tum
    • Disease : Progressive Myo
  • Slc6a1-KO

    Slc6a1-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Slc6a1t
    • Exon : Exon 2-3.
    • Application : Nervous System,
    • Disease : Schizophrenia
  • Slc37a4-KO

    Slc37a4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3
    • Application : Nervous System,
    • Disease : Glycogen Storag
  • Smad4-Flox

    Smad4-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sm
    • Exon : Exon 3-4
    • Application : Nervous System,
    • Disease : Osteogenesis Im
  • Slc9a9-KO

    Slc9a9-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 2
    • Application : Nervous System,
    • Disease : autism spectrum
  • Syn1-KO

    Syn1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sy
    • Exon : Exon 4
    • Application : Nervous System,
    • Disease : Epilepsy
  • Stat1-KO

    Stat1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 4-5
    • Application : Cancer Research
    • Disease : Severe Acute Re
  • Tgm2-KO

    Tgm2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Exon : Exon 3-4
    • Application : Apoptosis, Gluc
    • Disease : Maturity-Onset
  • Tfam-Flox

    Tfam-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tf
    • Exon : Exon 10-13
    • Application : Activated Pkn1
    • Disease : Parkinson's Dis
  • Yme1l1-Flox

    Yme1l1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ym
    • Exon : Exon s
    • Application : Activated Pkn1
    • Disease : Dilated Cardiom
  • Usp1-Flox

    Usp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Us
    • Exon : Exon 3
    • Application : Diseases Associ
    • Disease : Fanconi Anemia
  • Tyk2-KO

    Tyk2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ty
    • Exon : Exon 4
    • Application : Diseases Associ
    • Disease : Obesity