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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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Itgam-IRES-hCD89/hIGHA1
- Description : Itgam-IRES-hCD8
- Nomenclature : C57BL/6Smoc-Itg
- Strain : Repository Live
- KI/KO Gene : Itgam
- Synonyms : CR3; CR3A; MA
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R26-LSL-hIL15-Flag-IRES-EGFP
- Description : CAG-Loxp-Stop-L
- Nomenclature : C57BL/6Smoc-Gt(
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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hPD-1/hSIRPA(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hTIGIT
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-L1/hLAG3
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : LAG3
- Synonyms : Ly66; CD223;
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hPD-L1/hVEGFR2
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/hTIM3
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPSGL-1(2)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Sel
- Strain : Embryo cryopres
- KI/KO Gene : Selplg
- Synonyms : CD162; Psgl1; S
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hSIRPA(2)/hCD47/hPD-L1
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)
- Description : hSIRPA(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hSTING(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-tm
- Strain : Embryo cryopres
- KI/KO Gene : Tmem173
- Synonyms : ERIS; MPYS; M
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hTIGIT/hCCR8
- Description : hTIGIT(NM-HU-00
- Nomenclature : C57BL/6Smoc-Tig
- Strain : Embryo cryopres
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hIL21/hIL21R
- Description : hIL21(NM-HU-200
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL21
- Synonyms : IL-21
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hIL2/hIL2RA/hIL2RB/hIL2RG
- Description : hIL2/hIL2RA(NM-
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2
- Synonyms : Il-2
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