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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hGDF15/hPD-1/hPD-L1
- Description : hGDF15(NM-HU-21
- Nomenclature : C57BL/6Smoc-Gdf
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hICOS/hICOSL
- Description : This ICOS and I
- Nomenclature : C57BL/6Smoc-Ico
- Strain : Repository Live
- KI/KO Gene : ICOS
- Synonyms : AILIM; CCLP;
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hIL13/hOX40
- Description : hIL13(NM-HU-190
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Embryo cryopres
- KI/KO Gene : IL13
- Synonyms : IL-13; P600
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hIL13(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Embryo cryopres
- KI/KO Gene : IL13
- Synonyms : IL-13; P600
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hIL17RB(2)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Il1
- Strain : Embryo cryopres
- KI/KO Gene : Il17rb
- Synonyms : Evi27, Il17br,
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H11-pT3(b)-hIL15-Flag
- Description : pT3(b)-Kozak-hI
- Nomenclature : C57BL/6Smoc-Igs
- Strain : Sperm cryoprese
- KI/KO Gene : Igs2
- Synonyms : H11,Hipp11,Iis2
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hACE2-IRES-Luc-hAXL-Tg
- Description : These transgeni
- Nomenclature : C57BL/6Smoc-Tg(
- Strain : Developing
- KI/KO Gene : ACE2
- Synonyms : ACEH
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hAppNL-G-F
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-App
- Strain : Embryo cryopres
- KI/KO Gene : App
- Synonyms : Ag; Abpp; Adap;
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hALB/hFCRN
- Description : hALB(NM-HU-2000
- Nomenclature : C57BL/6Smoc-Alb
- Strain : Repository Live
- KI/KO Gene : FCGRT
- Synonyms : FcRn
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hCCR8/hCTLA-4
- Description : hCCR8(NM-HU-190
- Nomenclature : C57BL/6Smoc-Ccr
- Strain : Embryo cryopres
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hCCR8(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cc
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hPD-1/hLAG3
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Synonyms : Ly66; CD223;
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hPD-1/hPD-L1/hTIGIT
- Description : hTIGIT(NM-HU-00
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hPD-L1/hLAG3
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Synonyms : Ly66; CD223;
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hPD-L1/hOX40
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Synonyms : Ox40; ACT35;
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hPD-L1/hVISTA
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Vis
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/hSTING
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Tme
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/hSIGLEC15
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hSIRPA(2)/hCD47/hPD-1
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hSIRPA/hCD47(BALB/c)
- Description : hCD47 (NM-HU-00
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Repository Live
- KI/KO Gene : SIRPA
- Synonyms : Bit; P84; SIR
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hIL2 SP-hIL15-Tg(NMG)
- Description : These transgeni
- Nomenclature : NOD-PrkdcscidIl
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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hIL2RB/hPD-1
- Description : hIL2RB(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2RB
- Synonyms : p70; CD122; I
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hIL2RA/hCCR8
- Description : hIL2RA(NM-HU-19
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hIL2RG/hIL2RB
- Description : hIL2RG(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2RB
- Synonyms : p70; CD122; I
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hIL6/hIL6R
- Description : This IL6 and IL
- Nomenclature : C57BL/6Smoc-Il6
- Strain : Repository Live
- KI/KO Gene : IL6
- Synonyms : Il; Il-6
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hIL5/hIL5R(3)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Il5
- Strain : Repository Live
- KI/KO Gene : IL5
- Synonyms : Il-5
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