The endogenous mouse Ctal4 gene was replaced by human CTLA4 gene. While hCTLA4(2)(Stock No.NM-HU-190038) mice function similarly to hCTLA4 mice,for more detailed information please contact our technical advisor.
NCBI ID: 12477
MGI ID: 88556
Ensembl ID: ENSMUSG00000026011
Pubmed: CTLA4
Human Ortholog: CTLA4
Nomenclature
C57BL/6Smoc-Ctla4em1(hCTLA4) Smoc
Strain
Embryo cryopreservation
KI/KO Gene
CTLA4
Synonyms
Cd152; Ly-56; Ctla-4
Research Application
Drug screening, Immunotherapy, Cancer Research, Humanized Drug Targets