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Cenpf-Flox

SKU : BHAM00060

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Shanghai Model Organisms Center, Inc.

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Mfr.No.	NM-CKO-220268
Description	Model Description: These mice carry loxP sites flanking exon3 of Cenpf When crossed with a Cre recombinase-expressing strain, this strain is useful in eliminating tissue-specific conditional expression of Cenpf gene. Official Symbol: Cenpf NCBI ID: 108000 MGI ID: 1313302 Ensembl ID: ENSMUSG00000026605 Pubmed: Cenpf Human Ortholog: CENPF
Nomenclature	C57BL/6JSmoc-Cenpf^{em(flox)/Smoc}
Exon	Exon 3
Disease	Dilated Cardiomyopathy
Disease	Cardio-metabolic Disease
KI/KO Gene	Cenpf
Notes	Note: The expected phenotype(s) may be observed in the above-mentioned mice that bred with Tnnt2-cre mice.
Synonyms	CENF, Lek1, PRO1779, mitosin, AI325968, 6530404A22Rik

Reference	MGI:6189107 Dees E, Miller PM, Moynihan KL, Pooley RD, Hunt RP, Galindo CL, Rottman JN, Bader DM, Cardiac-specific deletion of the microtubule-binding protein CENP-F causes dilated cardiomyopathy. Dis Model Mech. 2012 Jul;5(4):468-80

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