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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIL2RA/hTNFRSF1B
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : TNFRSF1B
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hIL36A/hIL36B/hIL36G
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Il1f6
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hPVRL2/hPVRIG
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ne
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Pvrig
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hSIRPA/hCD47(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : SIRPA
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hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
-
hTIGIT/hPVR
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ti
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TIGIT
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