hFCRN

Mfr.No.	NM-HU-00109
Description	This FcRn humanized strain is established by mating endogenous mouse Fcgrt gene Knockout mice with R26-hFcRn(FCGRT) Knock-in mice. These FcRn humanized mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations. While hFCRN(2)(Stock No.NM-HU-190070) and hFCRN(3)(Stock No.NM-HU-2000032)mice function similarly to hFCRN mice,for more detailed information please contact our technical advisor. NCBI ID: 14132 MGI ID: 103017 Ensembl ID: ENSMUSG00000003420 Pubmed: FCGRT Human Ortholog: FCGRT
Nomenclature	C57BL/6Smoc-Gt(ROSA)26Sor^{em1(CAG-hFcRn)}Fcgrt^em1/Smoc
Strain	Embryo cryopreservation
KI/KO Gene	FCGRT
Synonyms	FcRn

Research Application	Drug screening, Immunotherapy, Cancer Research, Humanized Drug Targets

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