Purified recombinant fragment of human RAG1 (AA: 818-868) expressed in E. Coli.
Purification
Purified from ascites by Protein G chromatography.
Isotype
IgG
Tested Application
ELISA, WB
Uniprotkb
P15918 (UniProt, ExPASy)
Gene Id
5896
Availability
Shipped within 5-10 working days.
Concentration
1 mg/ml
Target
RAG1
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Reactivity
Human
Molecular Weight
119 kDa
uniprot enrty name
RAG1_HUMAN
Note
This product is for research use only.
Clonality
monoclonal
Buffer
PBS, containing 0.05% sodium azide.
Recommended Dilution
ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Description
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
Western blot analysis using RAG1 antibody against HEK293 (1) and RAG1 (AA: 818-868) -hIgGFc transfected HEK293 (2) cell lysate.