This ICOS and ICOSL double knockin strain is established by crossing ICOS-HU and ICOSL-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
NCBI ID: 54167
MGI ID: 1858745
Ensembl ID: ENSMUSG00000026009
Pubmed: ICOS
Human Ortholog: ICOS
Nomenclature
C57BL/6Smoc-Icoslem1(hICOSLG) Icosem1(hICOS)/Smoc
Strain
Repository Live
KI/KO Gene
ICOS
Synonyms
AILIM; CCLP; CRP-1; H4; Ly115
Research Application
Drug screening, Immunotherapy, Cancer Research, Humanized Drug Targets