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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hSIRPA(2)/hCD47/hPD-1/hPD-L1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hSIRPA(2)/hCD47
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : SIRPA
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hTLR8/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tl
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hTNFRSF1B/hFCGR2B
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Fcgr2b
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hTNFSF15(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Tnfsf15
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R26-CAG-LSL-hPLA2R1-IRES-EGFP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Gt
- Strain : Developing
- Target : Other Targets
- KI/KO Gene : Pla2r1
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Itgam-IRES-hCD89/hMASP2
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-It
- Strain : Developing
- Target : Other Targets
- KI/KO Gene : Itgam
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Rag2/IL2rg-KO/hSIRPA(2)/hCD47
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : IL2RG
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Rag2-KO/hKDR
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Kd
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Rag2
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R26-LSL-hIL5(M-NSG)
- Description : Model Descripti
- Nomenclature : NOD-PrkdcscidIl
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Gt(ROSA)26Sor
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