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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIL2(M-NSG,2)
- Description : Model Descripti
- Nomenclature : M-NSG-Il2tm(hIL
- Strain : Repository Live
- KI/KO Gene : Il2
- Synonyms : Il-2
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hENTPD1(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-En
- Strain : Developing
- KI/KO Gene : Entpd1
- Synonyms : Cd39, AA408691,
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hCD27/hPD-L1(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD27
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hCD3E/hCD3D/hCD3G
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD3EDG/hPSMA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hADORA2B(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ad
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Adora2b
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hSIRPA(2)/hCD47/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hTHPO(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Thpotm(hT
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Thpo
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hTLR8/Lyz2-DTREGFP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ly
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TLR8
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hTNFRSF13C
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Tnfrsf13c
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hTNFRSF1B/hPD-1/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Pdcd1
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hTNFRSF1B/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokine Recept
- KI/KO Gene : Pdcd1
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hTSLP(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Tslptm(hT
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Tslp
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pAtp4b-hCLDN18.2-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : Tslp
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pAlb-hLPA-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Repository Live
- Target : Metabolic Targe
- KI/KO Gene : LPA
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Rag2/IL2rg-KO/hKDR
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Repository Live
- Target : Metabolic Targe
- KI/KO Gene : IL2RG
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R26-LSL-hIL4(M-NSG)
- Description : Model Descripti
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : Gt(ROSA)26Sor
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Rag2-KO/hVEGFR2
- Description : The Rag2 gene o
- Nomenclature : C57BL/6Smoc-Kdr
- Strain : Embryo cryopres
- Target : Metabolic Targe
- KI/KO Gene : Rag2
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