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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIL2/hIL2RA(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : IL2
- Synonyms : Il-2
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hIL5/hIL5R(2)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Il5
- Strain : Repository Live
- KI/KO Gene : IL5
- Synonyms : Il-5
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hIL4-Tg(NMG)(2)
- Description : These transgeni
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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CAG-hACE2-IRES-Luc-Tg
- Description : The transgene i
- Nomenclature : C57BL/6Smoc-Tgt
- Strain : Repository Live
- KI/KO Gene : Nrp1
- Synonyms : ACEH
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h4-1BB(2)/hOX40
- Description : hTNFRSF9(NM-HU-
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : 4-1BB
- Synonyms : ILA; Ly63; 4-
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hB7H3/hPD-1
- Description : hB7-H3(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : CD276
- Synonyms : B7H3; B7-h3; B
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hB7H3/hCD28
- Description : hB7-H3(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : CD276
- Synonyms : B7H3; B7-h3; B
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hB2M-HLA A2.1(NMG)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- KI/KO Gene : H2-D1
- Synonyms : H-2D,H2-D,H2-K1
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hCD3E/hSDC1
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD3E/hCD20(2)
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD3EDG/hCD28/hCD38(2)
- Description : hCD3EDG/hCD28(N
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD28
- Synonyms : CD3 T3e AI50478
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hCD3EDG(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/c-Cd3etm1(
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD40L(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Embryo cryopres
- KI/KO Gene : Cd40lg
- Synonyms : IGM, IMD3, Ly62
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hCD81/hOCLN
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Cd8
- Strain : Embryo cryopres
- KI/KO Gene : CD81
- Synonyms : Tapa1; Tapa-1;
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hCSF1(NMG)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- KI/KO Gene : Csf1
- Synonyms : op,Csfm,MCSF,C8
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hCTLA-4/Cd8a-IRES-Luc-2A-EGFP
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : Cd8a
- Synonyms : Ly-2; Ly-B; L
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hLILRB1-hLILRB4-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Repository Live
- Target : Cytokine Recept
- KI/KO Gene : LILRB4
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hMS4A1(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ms
- Strain : Repository Live
- Target : Cytokine Recept
- KI/KO Gene : Ms4a1
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