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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hSIRPA(2)/hCD47/hPD-1
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hSIRPA/hCD47(BALB/c)
- Description : hCD47 (NM-HU-00
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Repository Live
- KI/KO Gene : SIRPA
- Synonyms : Bit; P84; SIR
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hIL2 SP-hIL15-Tg(NMG)
- Description : These transgeni
- Nomenclature : NOD-PrkdcscidIl
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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hIL2RB/hPD-1
- Description : hIL2RB(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2RB
- Synonyms : p70; CD122; I
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hIL2RA/hCCR8
- Description : hIL2RA(NM-HU-19
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hIL2RG/hIL2RB
- Description : hIL2RG(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2RB
- Synonyms : p70; CD122; I
-
hIL6/hIL6R
- Description : This IL6 and IL
- Nomenclature : C57BL/6Smoc-Il6
- Strain : Repository Live
- KI/KO Gene : IL6
- Synonyms : Il; Il-6
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hIL5/hIL5R(3)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Il5
- Strain : Repository Live
- KI/KO Gene : IL5
- Synonyms : Il-5
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hLAG3/hCTLA-4
- Description : This LAG3 and C
- Nomenclature : B6.129S-Lag3tm1
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hLAG3(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-La
- Strain : Developing
- KI/KO Gene : Lag3
- Synonyms : Ly66, CD223, LA
-
hOX40/hOX40L(2)
- Description : hTNFSF4(NM-HU-2
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : Ncr1
- Synonyms : Ath1, gp34, Ath
-
hPD-1/hCTLA-4
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
-
hPD-1/hCD40
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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