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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTIGIT/hPVR
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Tig
- Strain : Embryo cryopres
- KI/KO Gene : TIGIT
- Synonyms : Vstm3
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hCD19/hCD3E
- Description : This CD19 and C
- Nomenclature : C57BL/6Smoc-Cd1
- Strain : Embryo cryopres
- KI/KO Gene : CD19
- Synonyms : AW495831
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hCD3E/hCD28
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- KI/KO Gene : CD28
- Synonyms : Tspan26
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hCD3EDG/hCD20(2)
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD40/h4-1BB(2)
- Description : hCD40(NM-HU-000
- Nomenclature : C57BL/6Smoc-Cd4
- Strain : Repository Live
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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hCD40(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Synonyms : IGM; p50; Bp5
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hCD3EDG/hTPBG
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCTLA-4/h4-1BB(2)
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
-
hCTLA-4(BALB/c)
- Description : Obtained by bac
- Nomenclature : BALB/cAnSmoc-Ct
- Strain : Repository Live
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hB2M/HLA-A2
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-H2-
- Strain : Repository Live
- KI/KO Gene : H2-D1
- Synonyms : H-2D; H2-D; H
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