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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-1/hCTLA-4(BALB/c)
- Description : hPD-1(NM-HU-190
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hPD-1/hCD27(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : CD27
- Synonyms : Cd27; S152; T
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hPD-1/hPD-L1/hCD73(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hIL17RA(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : IL17RA
- Synonyms : Il17r; Cdw217
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hPD-1/hSIGLEC15
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hPD-L1/hPD-L2
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-L1(2)/hCCR8
- Description : hPD-1(2)(NM-HU-
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-1/hVISTA
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Vis
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hTLR9
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-L1/hSEMA4D
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/h4-1BB(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/hTIGIT
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P