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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hSIGLEC15(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Repository Live
- KI/KO Gene : SIGLEC15
- Synonyms : Cd33l3; EG6202
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hSIRPA(BALB/c,2)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- KI/KO Gene : IL11
- Synonyms : IL-11
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hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Description : hSIRPA(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hSIGLEC8(2)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Sig
- Strain : Embryo cryopres
- KI/KO Gene : Siglecf
- Synonyms : Siglec5; mSigle
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hTIGIT(BALB/c,2)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Ti
- Strain : Repository Live
- KI/KO Gene : Tigit
- Synonyms : Vstm3
-
hIL23A(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- KI/KO Gene : Il23a
- Synonyms : p19,IL-23
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hIL3/hCSF2
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Il3
- Strain : Repository Live
- KI/KO Gene : IL3
- Synonyms : BPA; PSF; HCG
-
hKITLG(NMG)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- KI/KO Gene : Kitl
- Synonyms : Gb, SF, Sl, Clo
-
hNKG2A/hCD94
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Nkg
- Strain : Embryo cryopres
- KI/KO Gene : Nr1i3
- Synonyms : NKG2A; NKG2B; C
-
hOX40/hCTLA-4
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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