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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTIGIT/hPVR
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ti
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TIGIT
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hTNFRSF1B(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Tn
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tnfrsf1b
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hTNFRSF10C
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tnfrsf23
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hIL6/hIL6R(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il6tm(hIL
- Strain : Repository Live
- Target : Tumor Targets
- KI/KO Gene : Tpbg
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hNCR3LG1-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tgtn( hNCR3LG1)
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hCD27(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD27
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hCD3E/hLAG3
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD3EDG/hCD40/h4-1BB(2)
- Description : hCD3EDG/hCD40(N
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD3EDG/hCD40
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD28
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hCD3EDG/hCD38(2)
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD3EDG/hCD19
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : CD19
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hCD3EDG/h4-1BB(2)
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD3EDG/hPD-L1
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD3EDG/hEpCAM
- Description : hCD3EDG(NM-HU-2
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hCD47(Balb/c,2)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CD47
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hTNFSF11/hSIGLEC15
- Description : hTNFSF11(NM-HU-
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : SIRPA
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Itgam-IRES-hCD89/hIGHA1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-It
- Strain : Repository Live
- Target : Other Targets
- KI/KO Gene : Itgam
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R26-LSL-hIL2 SP-hIL15(M-NSG)
- Description : Model Descripti
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- Target : Other Targets
- KI/KO Gene : Gt(ROSA)26Sor
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Rag2/IL2rg-KO/hCD40
- Description : The Rag2 and Il
- Nomenclature : C57BL/6Smoc-Cd4
- Strain : Developing
- Target : Other Targets
- KI/KO Gene : CD40
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hFCGR2B/h4-1BB(2)
- Description : hFCGR2B(NM-HU-2
- Nomenclature : C57BL/6Smoc-Fcg
- Strain : Embryo cryopres
- Target : Other Targets
- KI/KO Gene : Fcgr2b
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