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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-1/hPD-L1/hCTLA-4
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)
- Description : hSIRPA/hCD47(BA
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Developing
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hPD-L1(BALB/c)
- Description : hPD-1(BALB/c)(N
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hTLR8/hPD-1
- Description : hTLR8(NM-HU-190
- Nomenclature : C57BL/6Smoc-Tlr
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hTNFR2/hIL2RA
- Description : hTNFRSF1B(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : IL2RA
- Synonyms : CD25; Il2r; I
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hPD-1/hIL1B
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hSEMA4D
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hPD-1/hPD-L1/hOX40
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Synonyms : Ox40; ACT35;
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hPD-1/hVEGFR2
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
-
hPD-1/hTIM3
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
-
hPD-L1/hCTLA-4
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
-
hPD-L1/hCD73(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hPD-L1/hCD28
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
-
hPD-L2(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1lg2
- Synonyms : Btdc; B7-DC;
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hPD-L1/hSIRPA(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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