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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCsf1/hCsf1r(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cs
- Strain : Repository Live
- KI/KO Gene : CSF1
- Synonyms : colony-stimulat
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hCSF1/hCSF1R(2)
- Description : hCSF1(NM-HU-190
- Nomenclature : C57BL/6Smoc-Csf
- Strain : Embryo cryopres
- KI/KO Gene : CSF1
- Synonyms : colony-stimulat
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hCTLA-4/hTIGIT
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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hCTLA-4/hCCR8(BALB/c)
- Description : hCTLA4(BALB/c)(
- Nomenclature : BALB/cAnSmoc-Cc
- Strain : Repository Live
- KI/KO Gene : CCR8
- Synonyms : Cmkbr8
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hCTLA-4/4-1BB
- Description : This CTLA4 and
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Synonyms : Cd152; Ly-56;
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h4-1BB(2)/hPD-1
- Description : h4-1BB(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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h4-1BB(2)/hCD3E(2)
- Description : h4-1BB(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hB2M-HLA A2.1(NMG,2)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidIl
- Strain : Repository Live
- KI/KO Gene : B2m
- Synonyms : Ly-m11,beta2m,b
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hC5AR1/C5AR2
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-C5a
- Strain : Sperm cryoprese
- KI/KO Gene : C5AR1
- Synonyms : C5aR; C5r1; C
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