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Humanized Knockins

The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.

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  • pCdh16-hENPP3-Tg

    pCdh16-hENPP3-Tg

    pCdh16-hENPP3-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
  • pAlb-hAPOB-Tg

    pAlb-hAPOB-Tg

    pAlb-hAPOB-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : APOB
  • Ighm/Ighd-KO/hSIRPA/hCD47

    Ighm/Ighd-KO/hSIRPA/hCD47

    Ighm/Ighd-KO/hSIRPA/hCD47

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : SIRPA
  • Rag2/IL2rg-KO/hCD40

    Rag2/IL2rg-KO/hCD40

    Rag2/IL2rg-KO/hCD40

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : CD40
  • hCLDN18.2-Tg

    hCLDN18.2-Tg

    hCLDN18.2-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : CD40
  • hCXCR5

    hCXCR5

    hCXCR5

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cx
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Cxcr5
  • hENTPD1(2)

    hENTPD1(2)

    hENTPD1(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Entpd1
  • hF9

    hF9

    hF9

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F9
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : F9
  • hFCGR3A

    hFCGR3A

    hFCGR3A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fc
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Fcgr4
  • hFCGR1B

    hFCGR1B

    hFCGR1B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fc
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Fcgr1
  • hFOLR1

    hFOLR1

    hFOLR1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fo
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Folr1
  • hALDH2

    hALDH2

    hALDH2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Aldh2
  • hANGPTL3(5)

    hANGPTL3(5)

    hANGPTL3(5)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-An
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Angptl3
  • hC1QA(2)

    hC1QA(2)

    hC1QA(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C1
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : C1qa
  • hCCL2

    hCCL2

    hCCL2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cc
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Ccl2
  • hCCN4

    hCCN4

    hCCN4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cc
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Ccn4
  • hCD123

    hCD123

    hCD123

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Il3ra
  • hCCR8(BALB/c)(2)

    hCCR8(BALB/c)(2)

    hCCR8(BALB/c)(2)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cc
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Ccr8
  • hCD19-Tg

    hCD19-Tg

    hCD19-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Ccr8
  • hCD19

    hCD19

    hCD19

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Embryo cryopres
    • Target : Tumor Targets
    • KI/KO Gene : Cd19
  • hCD24(3)

    hCD24(3)

    hCD24(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd24a
  • hCD40/hOX40

    hCD40/hOX40

    hCD40/hOX40

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : CD40
  • hCD6(2)

    hCD6(2)

    hCD6(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Cd6
  • hCD5(2)

    hCD5(2)

    hCD5(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Cd5
  • hFCGR2B/h4-1BB(2)

    hFCGR2B/h4-1BB(2)

    hFCGR2B/h4-1BB(2)

    • Description : hFCGR2B(NM-HU-2
    • Nomenclature : C57BL/6Smoc-Fcg
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Fcgr2b
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