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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-L1/hSIRPA(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Synonyms : B7h1; Pdl1; P
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hSIGLEC15(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Repository Live
- KI/KO Gene : SIGLEC15
- Synonyms : Cd33l3; EG6202
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hSIRPA(BALB/c,2)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- KI/KO Gene : IL11
- Synonyms : IL-11
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hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Description : hSIRPA(2)(NM-HU
- Nomenclature : C57BL/6Smoc-Sir
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1; Pdc1; Ly1
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hSIGLEC8(2)
- Description : The endogenous
- Nomenclature : C57BL/6Smoc-Sig
- Strain : Embryo cryopres
- KI/KO Gene : Siglecf
- Synonyms : Siglec5; mSigle
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hTIGIT(BALB/c,2)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Ti
- Strain : Repository Live
- KI/KO Gene : Tigit
- Synonyms : Vstm3
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hCTLA-4/hCD28(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ct
- Strain : Embryo cryopres
- KI/KO Gene : CD28
- Synonyms : C7, IP10, CRG-2
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hGFRAL(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Gf
- Strain : Developing
- KI/KO Gene : Gfral
- Synonyms : Gral, AY457637
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hIL15RA(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Il
- Strain : Developing
- KI/KO Gene : Il15ra
- Synonyms : IL-15RA, AA6901
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hIL3/hCSF2(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Embryo cryopres
- KI/KO Gene : IL3
- Synonyms : BPA, PSF, HCG
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hCD19(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- KI/KO Gene : Cd19
- Synonyms : AW495831
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hCD28/hPD-1/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- KI/KO Gene : CD28
- Synonyms : AW495831
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hCD27/hPD-1(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- KI/KO Gene : CD27
- Synonyms : Cd27, S152, T
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hCD79A/hCD79B
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Embryo cryopres
- KI/KO Gene : CD79a
- Synonyms : Iga, Ly54, mb
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hANGPTL3(3)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-An
- Strain : Repository Live
- Target : Metabolic Targe
- KI/KO Gene : Angptl3
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hPD-L1(BALB/c,2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- Target : Other Targets
- KI/KO Gene : Cd274
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hSIRPA(BALB/c,2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Sirpa
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hSIRPA(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Sirpa
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