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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIL3/hCSF2(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il3tm(hIL
- Strain : Repository Live
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hIL5/hIL5RA(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Il5tm(hIL
- Strain : Repository Live
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hLILRB1-hLILRB2-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
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hIL2RA/hIL2RG
- Description : hIL2RG(NM-HU-20
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : IL2RA
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hIL21R/hIL2RG
- Description : hIL21R(NM-HU-21
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : IL21R
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hIL3/hCSF2/hCSF1
- Description : hIL3(NM-HU-1900
- Nomenclature : C57BL/6Smoc-Il3
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : CSF1
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hIL5-Tg(NMG,2)
- Description : These transgeni
- Nomenclature : NOD-PrkdcscidIl
- Strain : Sperm cryoprese
- Target : Tumor Targets
- KI/KO Gene : Gt(ROSA)26Sor
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hIL4/hIL4R(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- Target : Tumor Targets
- KI/KO Gene : IL4
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hIL9(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Il
- Strain : Repository Live
- Target : Tumor Targets
- KI/KO Gene : Il9
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hLAIR1/hPD-1/hPD-L1
- Description : hLAIR1(NM-HU-20
- Nomenclature : C57BL/6Smoc-Lai
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : LAIR1
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hPD-1/hICOS(2)
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : ICOS
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hPD-1/hCD3E
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : CD3E
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hPD-1/hCD28
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Repository Live
- Target : Tumor Targets
- KI/KO Gene : CD28
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hPD-1/Cd8a-IRES-Akaluc-2A-EGFP
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Mst1
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hPD-1/hPD-L1/hCTLA-4
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : CTLA4
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hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)
- Description : hSIRPA/hCD47(BA
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hPD-1/hPD-L1(BALB/c)
- Description : hPD-1(BALB/c)(N
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Repository Live
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hTLR8/hPD-1
- Description : hTLR8(NM-HU-190
- Nomenclature : C57BL/6Smoc-Tlr
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hTNFR2/hIL2RA
- Description : hTNFRSF1B(NM-HU
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : IL2RA
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hPD-1/hIL1B
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hPD-1/hSEMA4D
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hPD-1/hPD-L1/hOX40
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Tnf
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Tnfrsf4
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hPD-1/hVEGFR2
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hPD-1/hTIM3
- Description : hPD-1(NM-HU-000
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Pdcd1
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hPD-L1/hCTLA-4
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : CTLA4
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hPD-L1/hCD73(2)
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Cd274
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hPD-L1/hCD28
- Description : hPD-L1(NM-HU-00
- Nomenclature : C57BL/6Smoc-Cd2
- Strain : Repository Live
- Target : Tumor Targets
- KI/KO Gene : Cd274
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hPD-L2(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Pd
- Strain : Embryo cryopres
- Target : Tumor Targets
- KI/KO Gene : Pdcd1lg2
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