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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD27/hPD-L1(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Developing
- KI/KO Gene : CD27
- Synonyms : Cd27, S152, T
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hCD3E/hCD3D/hCD3G
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- KI/KO Gene : CD3E
- Synonyms : CD3, T3e, AI5
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hCD3EDG/hPSMA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CD3E
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hADORA2B(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ad
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Adora2b
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hSIRPA(2)/hCD47/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Cd274
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hTHPO(M-NSG)
- Description : Model Descripti
- Nomenclature : M-NSG-Thpotm(hT
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Thpo
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hTLR8/Lyz2-DTREGFP
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ly
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : TLR8
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hTNFRSF13C
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Tnfrsf13c
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hTNFRSF1B/hPD-1/hPD-L1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Pdcd1
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hTNFRSF1B/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokine Recept
- KI/KO Gene : Pdcd1
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