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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD47/hSIRPA(2)/hCD38(2)
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : SIRPA
- Strain : Developing
- Description : Model Descripti
- Synonyms : Bit, P84, SIR
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hCEACAM6-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- KI/KO Gene : Tgtn(hCEACAM6)1
- Strain : Developing
- Target : Tumor Targets
- Description : Model Descripti
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hADORA2A(BALB/c)
- Nomenclature : BALB/cAnSmoc-Ad
- KI/KO Gene : Adora2a
- Strain : Developing
- Description : Model Descripti
- Synonyms : A2AAR,A2aR,AA2A
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hIL2RA/hTNFRSF1B
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : TNFRSF1B
- Strain : Developing
- Description : Model Descripti
- Synonyms : p75, TNFBR, T
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hIL36A/hIL36B/hIL36G
- Nomenclature : C57BL/6JSmoc-Il
- KI/KO Gene : Il1f6
- Strain : Developing
- Description : Model Descripti
- Synonyms : Fil1, Il1f9, Il
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hPVRL2/hPVRIG
- Nomenclature : C57BL/6JSmoc-Ne
- KI/KO Gene : Pvrig
- Strain : Developing
- Description : Model Descripti
- Synonyms : Gm36869
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hSIRPA/hCD47(BALB/c)
- Nomenclature : BALB/cAnSmoc-Si
- KI/KO Gene : SIRPA
- Research Application : Tumor research
- Strain : Repository Live
- Target : Immune Checkpoi
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hSIRPA(2)/hCD47/hPD-1/hPD-L1
- Nomenclature : C57BL/6JSmoc-Si
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Strain : Repository Live
- Target : Immune Checkpoi