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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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h4-1BB(2)/hPD-1
- Strain : Repository Live
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tnf
- Description : h4-1BB(2)(NM-HU
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h4-1BB(2)/hCD3E(2)
- Strain : Repository Live
- KI/KO Gene : CD3E
- Research Application : Immunotherapy E
- Nomenclature : C57BL/6Smoc-Tnf
- Description : h4-1BB(2)(NM-HU
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hB2M-HLA A2.1(NMG,2)
- Strain : Repository Live
- KI/KO Gene : B2m
- Research Application : Humanized Drug
- Nomenclature : NOD-PrkdcscidIl
- Description : The endogenous
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hC5AR1/C5AR2
- Strain : Sperm cryoprese
- KI/KO Gene : C5AR1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-C5a
- Description : The endogenous
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hIL2RA/hIL2RG
- Strain : Embryo cryopres
- KI/KO Gene : IL2RA
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2RG(NM-HU-20
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hIL21R/hIL2RG
- Strain : Embryo cryopres
- KI/KO Gene : IL21R
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL21R(NM-HU-21
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hIL3/hCSF2/hCSF1
- Strain : Embryo cryopres
- KI/KO Gene : CSF1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il3
- Description : hIL3(NM-HU-1900
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hIL5-Tg(NMG,2)
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Research Application : Humanized Drug
- Nomenclature : NOD-PrkdcscidIl
- Description : These transgeni