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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hLAG3(BALB/c)
- Strain : Developing
- KI/KO Gene : Lag3
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-La
- Description : The endogenous
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hOX40/hOX40L(2)
- Strain : Embryo cryopres
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tnf
- Description : hTNFSF4(NM-HU-2
- Synonyms : Ath1, gp34, Ath
-
hPD-1/hCTLA-4
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Cancer Research
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hCD40
- Strain : Embryo cryopres
- KI/KO Gene : CD40
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hPD-L1(2)/hCCR8
- Strain : Developing
- KI/KO Gene : CD27
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hOX40
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Research Application : Cancer Research
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hCD27(BALB/c)
- Strain : Developing
- KI/KO Gene : CD27
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-Cd
- Description : The endogenous
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hCD3E/hLAG3
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3E(NM-HU-001
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hCD3EDG/hCD40/h4-1BB(2)
- Strain : Developing
- KI/KO Gene : CD3E
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG/hCD40(N
-
hCD3EDG/hCD40
- Strain : Developing
- KI/KO Gene : CD28
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG(NM-HU-2
-
hCD3EDG/hCD38(2)
- Strain : Developing
- KI/KO Gene : CD3E
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG(NM-HU-2
-
hCD3EDG/hCD19
- Strain : Repository Live
- KI/KO Gene : CD19
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG(NM-HU-2
-
hCD3EDG/h4-1BB(2)
- Strain : Repository Live
- KI/KO Gene : CD3E
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG(NM-HU-2
-
hCD3EDG/hPD-L1
- Strain : Repository Live
- KI/KO Gene : CD3E
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG(NM-HU-2