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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hPD-1/hLAG3
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hPD-L1/hTIGIT
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hTIGIT(NM-HU-00
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hPD-1/hPD-L1/hLAG3
- Strain : Embryo cryopres
- KI/KO Gene : LAG3
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-L1/hOX40
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Research Application : Cancer Research
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(NM-HU-00
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hPD-L1/hVISTA
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Vis
- Description : hPD-L1(NM-HU-00
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hPD-L1/hSTING
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tme
- Description : hPD-L1(NM-HU-00
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hPD-L1/hSIGLEC15
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-L1(NM-HU-00
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hSIRPA(2)/hCD47/hPD-1
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Sir
- Description : hPD-1(NM-HU-000
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hSIRPA/hCD47(BALB/c)
- Strain : Repository Live
- KI/KO Gene : SIRPA
- Research Application : Tumor Research
- Nomenclature : BALB/cAnSmoc-Si
- Description : hCD47 (NM-HU-00
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hIL2 SP-hIL15-Tg(NMG)
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Research Application : Humanized Drug
- Nomenclature : NOD-PrkdcscidIl
- Description : These transgeni
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hIL2RB/hPD-1
- Strain : Repository Live
- KI/KO Gene : IL2RB
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2RB(NM-HU-20
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hIL2RA/hCCR8
- Strain : Repository Live
- KI/KO Gene : CCR8
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2RA(NM-HU-19
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hIL2RG/hIL2RB
- Strain : Repository Live
- KI/KO Gene : IL2RB
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2RG(NM-HU-20
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hIL6/hIL6R
- Strain : Repository Live
- KI/KO Gene : IL6
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il6
- Description : This IL6 and IL
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hIL5/hIL5R(3)
- Strain : Repository Live
- KI/KO Gene : IL5
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Il5
- Description : The endogenous
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hLAG3/hCTLA-4
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Humanized Drug
- Nomenclature : B6.129S-Lag3tm1
- Description : This LAG3 and C