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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hNKG2A/hCD94
- Strain : Embryo cryopres
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Nkg
- Description : The endogenous
- Synonyms : NKG2A; NKG2B; C
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hOX40/hCTLA-4
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tnf
- Description : These mice are
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hPD-1/hCTLA-4(BALB/c)
- Strain : Embryo cryopres
- KI/KO Gene : CTLA4
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Pd
- Description : hPD-1(NM-HU-190
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hPD-1/hCD27(2)
- Strain : Embryo cryopres
- KI/KO Gene : CD27
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hPD-L1/hCD73(2)
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hIL17RA(BALB/c)
- Strain : Repository Live
- KI/KO Gene : IL17RA
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Il
- Description : The endogenous
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hPD-1/hSIGLEC15
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000
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hPD-1/hPD-L1/hPD-L2
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Pdc
- Description : The endogenous
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hPD-L1(2)/hCCR8
- Strain : Embryo cryopres
- KI/KO Gene : Cd274
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd2
- Description : hPD-1(2)(NM-HU-
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hPD-1/hVISTA
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Vis
- Description : hPD-1(NM-HU-000
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hPD-1/hTLR9
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Pdc
- Description : hPD-1(NM-HU-000