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Disease Mice

Shanghai Model Organisms Center, Inc.

Disease Mice

Mouse models are very useful because they share mammalian features with humans and suffer from many of the same diseases. Many mouse models have been created to target specific human diseases using genetic engineering.

  • Grm5-KO

    Grm5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gr
    • Exon : Exon 4
    • Application : Endocrine, Cort
    • Disease : Schizophrenia
  • Gpr143-KO

    Gpr143-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gp
    • Exon : Exon 2
    • Application : Endocrine, Cort
    • Disease : Ocular Albinism
  • hTNFa-Tg(DBA)

    hTNFa-Tg(DBA)

    • Description : Model Descripti
    • Nomenclature : DBA-Tg(hTNFa)1S
    • Exon : Exon 2
    • Application : Arthritis Mouse
    • Disease : Ocular Albinism
  • Hmga1-KO

    Hmga1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hm
    • Exon : Exon 3-5
    • Application : Arthritis Mouse
    • Disease : Type 2 Diabetes
  • Hivep2-KO

    Hivep2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hm
    • Exon : Exon 5
    • Application : Arthritis Mouse
    • Disease : Schizophrenia
  • Lat-Y136F

    Lat-Y136F

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-La
    • Exon : Exon 5
    • Application : Igg4-Related Di
    • Disease : Igg4-Related Di
  • Kras-LSL-G12D

    Kras-LSL-G12D

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kr
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Squamous Cell C
  • KPC(2)

    KPC(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 2
    • Application : Spontaneous Pan
    • Disease : pancreatic carc
  • Lmx1b-Flox

    Lmx1b-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon 4-6
    • Application : Research On Dop
    • Disease : Nail-Patella Sy
  • Lep-KO

    Lep-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Leptm1S
    • Exon : Exon 2
    • Application : Insulin Resista
    • Disease : Abdominal Obesi
  • Ldlr-KO(2)

    Ldlr-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ld
    • Exon : Exon 4.
    • Application : Insulin Resista
    • Disease : familial hyperc
  • Mecp2-Flox

    Mecp2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 2-3.
    • Application : Rett Syndrome,
    • Disease : Rett Syndrome
  • Mdm4-Flox

    Mdm4-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Md
    • Exon : Exon s
    • Application : Rett Syndrome,
    • Disease : Dilated Cardiom
  • Myocd-Flox

    Myocd-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-My
    • Exon : Exon s
    • Application : Rett Syndrome,
    • Disease : Patent Ductus A
  • Mertk-KO

    Mertk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 2
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Nipbl-Flox

    Nipbl-Flox

    • Description : Model Descripti
    • Nomenclature : B6;129S-Nipbltm
    • Exon : Exon 5
    • Application : Cornelia De Lan
    • Disease : Autoimmune Dise
  • Nexn-KO

    Nexn-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Nipbltm
    • Exon : Exon 5-13
    • Application : Cornelia De Lan
    • Disease : dilated cardiom
  • Nexmif-KO

    Nexmif-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 4
    • Application : Cornelia De Lan
    • Disease : Autism Spectrum
  • Nrcam-KO

    Nrcam-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 5
    • Application : Cornelia De Lan
    • Disease : Autism Spectrum
  • Nphs2-R231Q

    Nphs2-R231Q

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 5
    • Application : Cornelia De Lan
    • Disease : Hereditary Glom
  • Pah-KO

    Pah-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pa
    • Exon : Exon 2-5
    • Application : Cornelia De Lan
    • Disease : Phenylketonuria
  • Opg-KO

    Opg-KO

    • Description : Model Descripti
    • Nomenclature : B6.129S-Tnfrsf1
    • Exon : Exon 2
    • Application : Osteoporosis
    • Disease : Phenylketonuria
  • Nrxn1-KO

    Nrxn1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 6
    • Application : Osteoporosis
    • Disease : Schizophrenia
  • Nrp2-KO

    Nrp2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 2
    • Application : Osteoporosis
    • Disease : Autism Spectrum
  • Pink1-KO

    Pink1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pi
    • Exon : Exon 2-4
    • Application : Mitochondrial H
    • Disease : Parkinson's Dis