hSIRPA(2)/hCD47

Mfr.No.	NM-HU-2000111
Description	Model Description: This SIRPA and CD47 double Knock-in strain is established by crossing hSIRPA and hCD47 mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.While hSIRPA/hCD47 (Stock No.NM-HU-190019) have been pulled from shelves for some reasons. Official Symbol: SIRPA NCBI ID Link: 19261 MGI ID Link: 108563 Ensembl ID Link: ENSMUSG00000037902 Pubmed Link: SIRPA Human Ortholog: SIRPA
Nomenclature	C57BL/6JSmoc-Sirpa^tm2(hSIRPA)Cd47^{em1(hCD47)/Smoc}
Strain	Repository Live
Target	Immune Checkpoints
KI/KO Gene	SIRPA
Synonyms	Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480

Research Application	Cancer research, Drug screening, Immunotherapy
Applications	Immunotherapy, Cancer research, Drug screening

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