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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hIFNGR1/hIFNGR2
- Strain : Embryo cryopres
- KI/KO Gene : IFNGR1
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Ifn
- Description : hIFNGR1(NM-HU-1
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hIL12A/hIL12B/hIL12RB1/hIL12RB2
- Strain : Developing
- KI/KO Gene : Il12b
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il1
- Description : hIL12A(NM-HU-20
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hIL1B(BALB/c)
- Strain : Repository Live
- KI/KO Gene : IL1B
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Il
- Description : The endogenous
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hTLR9/hOX40
- Strain : Embryo cryopres
- KI/KO Gene : Tnfrsf4
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tlr
- Description : This TLR9 and O
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hTLR8/Lyz2-DTREGFP
- Strain : Embryo cryopres
- KI/KO Gene : TLR8
- Research Application : Tumor Research
- Nomenclature : C57BL/6Smoc-Lyz
- Description : NM-KI-190041 wa
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hTIGIT/hTNFR2
- Strain : Repository Live
- KI/KO Gene : CTLA4
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tig
- Description : hTIGIT(3)(NM-HU
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hTNFR2/hPD-1
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tnf
- Description : hTNFRSF1B(NM-HU
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hTSLP/hIL17RA
- Strain : Embryo cryopres
- KI/KO Gene : TSLP
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tsl
- Description : hTSLP(NM-HU-200