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MycoFold
4000 Mason Rd, Seattle, Washington, 98195, United States
MycoFold™
Better Recombinant Proteins by Design
Advanced yeast expression technology delivering superior bioactivity, purity, and value
View full product listAbout MycoFold
MycoFold represents a breakthrough in recombinant protein production. Founded by experienced leaders in Life Science Tools, the company addresses critical limitations of traditional expression systems (E. coli, HEK293, CHO) that have remained largely unchanged for 30 years.
Traditional protein expression models often produce incomplete, improperly folded, or unstable growth factors. MycoFold's proprietary yeast platform (K. phaffii) is genetically engineered to replicate human-like Post-Translational Modifications (PTM), ensuring proper 3D folding and maximum bioactivity.
The MycoFold Advantage
Superior Folding & Purity
Chaperone proteins in the ER perform quality control. Proteins secreted at ~90% purity with proper disulfide bridges and glycosylation patterns.
100% Animal-Free
Completely animal-origin free production with endotoxin-free output. Ideal for sensitive cell culture applications.
Enhanced Value
Up to 2-3x bioactivity per dollar compared to mammalian systems. Use up to 50% less protein per experiment.
Scalable & Stable
Thermal stability validated (Tm 79.2°C). Simple transition from RUO to GMP manufacturing.
Platform Comparison
MycoFold's yeast expression system bridges the gap between bacterial cost-efficiency and mammalian complexity:
| Feature | MycoFold | E. coli | HEK/CHO |
|---|---|---|---|
| Expression System | K. phaffii (Yeast) | Bacterial | Mammalian |
| Secretion Purity | ~90% | 20-40% | 50-65% |
| Animal Origin Free | ✓ Yes | ✓ Yes | ✗ No |
| Manufacturing Cost | $ Low | $$ Medium | $$$$ High |
Featured Products
High-performance cytokines and growth factors available in sizes from 10μg to 1mg:
M-CSF (Cat. No. GR1003)
Macrophage Colony-Stimulating Factor for differentiation of macrophages, microglia, and osteoclasts.
Applications: Oncology, Neurodegeneration, Bone Biology
PDGF-BB (Cat. No. GR1002)
Platelet-derived Growth Factor for wound healing and fibroblast proliferation.
Applications: Wound Healing, Stem Cell Maintenance
IL-2 (Cat. No. GR1004)
Interleukin-2 cytokine for T-cell proliferation and immunotherapy research.
Applications: Immunology, Cancer Immunotherapy
IL-6 (Cat. No. GR1005)
Interleukin-6 for B-cell differentiation and inflammation research.
Applications: Inflammation, B-cell Biology
Why Choose MycoFold?
|
✓Use up to 50% less protein per experiment ✓2.0-3.0x bioactivity value per dollar spent ✓Enhanced thermal stability (Tm 79.2°C) ✓Fully documented QC with mass spec analysis |
✓Ambient temperature shipping (lyophilized) ✓Simple reconstitution - no complex supplements ✓100% animal-free production process ✓Seamless RUO to GMP scale-up |
Ready to Upgrade Your Research?
Experience the difference of properly folded, high-bioactivity recombinant proteins.
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