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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Zebrafish AXIN2 Antibody

SKU : BHA21011338

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Mfr.No.	AZP57095
Background	Axin-2 also known as axin-like protein (Axil) or axis inhibition protein 2 (AXIN2) or conductin is a protein that in humans is encoded by the AXIN2 gene. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.
Antibody Validation	Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Clonality	Polyclonal
Description	Boster Bio Anti-Zebrafish AXIN2 Antibody catalog #AZP57095. Tested in IHC applications. This antibody reacts with Zebrafish.
Host	Rabbit
Immunogen Region	E.coli-derived zebrafish AXIN2 recombinant protein (Position: H86-D812)
Positive Control	IHC: zebrafish colon tissue, zebrafish spinal cord tissue
Reactivity	Zebrafish
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Target Details	Axin-2
Gene Name	AXIN2
Weight	93.558kDa

Dilutions	Immunohistochemistry, 2-5 ?g/ml, Zebrafish
Form	Lyophilized
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	IHC
Description	AZP57095 is guaranteed for IHC Boster Guarantee

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21011338-1	AZP57095	Unconjugated	100 ug	$470		Add to Cart
BHA21011338-2	AZP57095-Biotin	Biotin conjugated	100 ug	$670		Add to Cart
BHA21011338-3	AZP57095-Cy3	Cy3 conjugated	100 ug	$670		Add to Cart
BHA21011338-4	AZP57095-Dylight488	Dylight488 conjugated	100 ug	$670		Add to Cart
BHA21011338-5	AZP57095-Dylight550	Dylight550 conjugated	100 ug	$670		Add to Cart
BHA21011338-6	AZP57095-Dylight594	Dylight594 conjugated	100 ug	$670		Add to Cart
BHA21011338-7	AZP57095-FITC	FITC conjugated	100 ug	$670		Add to Cart
BHA21011338-8	AZP57095-HRP	HRP conjugated	100 ug	$670		Add to Cart
BHA21011338-9	AZP57095-APC	APC conjugated	100 ug	$770		Add to Cart
BHA21011338-10	AZP57095-PE	PE conjugated	100 ug	$770		Add to Cart
BHA21011338-11	AZP57095-iFluor647	iFluor647 conjugated	100 ug	$770		Add to Cart
BHA21011338-12	AZP57095-carrier-free	Carrier Free	100 ug	$470		Add to Cart

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