v-myb myeloblastosis viral oncogene homolog (avian) Adenovirus (Ad-c-Myb)

Mfr.No.	1469
Description	The Myb family of transcription factors regulate differentiation and cellular growth through binding to promoters with the consensus sequence 5'-AAC(G/T)G-3' and transactivating gene expression. The proto-oncogene c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc, and c-Myc is expressed predominantly in immature and rapidly dividing hematopoietic cells. Additional members of the family include B-Myb, a 110 kDa protein that is expressed in a wide variety of proliferating cells at the G1 to S phase transition, and A-Myb, which is expressed in reproductive tissues, some neural cells and a subset of normal and neoplastic B lymphocytes. Transactivation properties of B-Myb are apparently dependent upon the protein's hyperphosphorylation at several C-terminal residues, including Thr 447, Thr 490, Thr 497 and Ser 581. Dmp1 is related to the Myb family and also functions as a transcriptional activator. Dmp1 contains three tandem Myb repeats and is a putative substrate for cyclin D-dependent kinase.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	c-Myb
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600165	1469	200 µL	$690		Add to Cart