TNF receptor-associated factor 4 Adenovirus (Ad-TRAF4)

Mfr.No.	1511
Description	TNF receptor-associated factors 1 and 2 (TRAF1 and TRAF2) are two related proteins that form a heterodimeric complex that associates with the cytoplasmic domain of the tumor necrosis factor (TNF) receptor type 2. A third member of this family, TRAF3 (also designated CD40bp or CRAF1), associates with the cytoplasmic domain of CD40. Three additional members of the TRAF/CRAF family of signaling intermediates include TRAF4 (also designated CART1), TRAF5 and TRAF6. TRAF4 has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Promoter	CMV (ubiquitous)
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	TRAF4
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Storage	-80C
Shipping	Dry Ice

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHV21600206	1511	200 µL	$690		Add to Cart